The early-warning gap

Heart failure worsens before resting signals make it obvious.

Passive monitoring can miss deterioration, create alert noise, or warn too late.

Missed changeAlert noiseLate action

U.S. BURDEN · 2025 EVIDENCE

The window matters because the burden is already massive.

Earlier warning means a chance to act before another costly admission.

6.7MAmericans living with heart failure
1.2Mprimary heart failure hospitalizations annually
16.7–31.2%reported 90-day readmission range
$10.7–17.8Kmean cost range per readmission
$18.5Bannual U.S. hospitalization cost

U.S. evidence published in 2025: HFSA Heart Failure Stats 2025, 2025 economic analysis and 2025 national hospitalization-cost study. Underlying datasets and cost bases may precede publication.

WHY PASSIVE-ONLY FALLS SHORT

More resting data does not reveal physiological reserve.

01 / MISS

Resting signals can look acceptable while reserve is declining.

02 / NOISE

Thresholds can create alerts without actionable deterioration.

03 / LATE

The signal may become obvious only after the intervention window narrows.

Evidence examples include an algorithm with 34% sensitivity and 2.4 false-positive alerts per patient-year, and a study in which 79.2% of alerts that triggered office visits showed no cardiac decompensation. Sources: Journal of Cardiac Failure and peer-reviewed review.

The 72Ahead difference

Passive first.
Active when it matters.

SAME PATIENTDifferent information
PASSIVE VIEWLooks stable
TRIGGERED CHECK
RESPONSE VIEWReserve exposed
Hemodynamic responseAutonomic adaptationRecovery kinetics
STAGE 01PASSIVE

Learn the personal baseline.

Daily life. Individual trajectory. Continuous context.

DEVIATIONTrigger
STAGE 02ACTIVE

Reveal the hidden reserve.

Brief guided check. Response. Adaptation. Recovery.

WHAT PASSIVE DATA CANNOT GENERATE ALONEHemodynamic responseAutonomic adaptationRecovery kinetics

The new vital sign

Not just the state of the body.
Its ability to respond.

72Ahead is building a home-monitoring platform that adds the missing physiological assessment layer to passive monitoring.

01Response
02Adaptation
03Recovery
04Trajectory

Momentum

Already moving into clinical reality.

BuiltWorking end-to-end platform
ProtectedPatent applications filed
BackedIsrael Innovation Authority grant
UnderwayClinical feasibility study at a heart failure institute

Shape the next standard
in heart failure care.

We are engaging with people who recognize the value of acting earlier.

Clinical leadersStrategic partnersInvestorsPatients & caregivers
Explore a collaboration